FA10 Rabbit Polyclonal Antibody

SKU: BT-AP02560

Size:100μL

Background:Catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.|Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va| calcium and phospholipid during blood clotting.|online information:Factor X entry|PTM:N- and O-glycosylated.|PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway)| or by factor VIIa (in the extrinsic pathway).|PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.|PTM:The vitamin K-dependent| enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.|Belongs to the peptidase S1 family.|Contains 1 Gla (gamma-carboxy-glutamate) domain.|Contains 1 peptidase S1 domain.|Contains 2 EGF-like domains.|subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.|tissue specificity:Plasma; synthesized in the liver.|

Research_area:Cardiovascular

Target_protein:F10

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:FA10

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):53680

UniProt accession:Human: P00742; Mouse: O88947; Rat: Q63207

Synonyms:FA10 ;light chain; Cleaved-Arg179; Coagulation factor X; EC 3.4.21.6; Stuart factor; Stuart-Prower factor; Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain;

GeneID:Human: 2159; Mouse: 14058; Rat: 29243