EXD2 Polyclonal Antibody

SKU: E-AB-18841

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: EXD2

Target Synonym: 4930539P14Rik;C14orf114;C85658;DKFZp781A0133;DKFZp781L15100;Exd2;EXD2;EXDL2;Exonuclease 3''-5'' domain-containing protein 2;Exonuclease 3''-5'' domain-like-containing protein 2;exonuclease 3'-5' domain-like 2;FLJ10738;RGD1311087

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9NVH0

Accession:

Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Concentration: 0.96 mg/mL

Immunogen: Fusion protein of human EXD2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:40-1:200

Calculated MW: 70 kDa

ObservedMW: Refer to figures