ERCC4 rabbit pAb

SKU: ES2292

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Mouse

Dilution:Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human XPF. AA range:801-850

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):103kD

Human_gene_id:2072

Human_swiss_prot_no:Q92889

Subcellular_location:Nucleus . Chromosome . Localizes to sites of DNA damage. .

Other_name:ERCC4; ERCC11; XPF; DNA repair endonuclease XPF; DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein

Background:The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009],