EEF1E1 Polyclonal Antibody

SKU: E-AB-52323

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:EEF1E1

Target Synonym:AIMP 3;AIMP3;Aminoacyl tRNA synthetase complex interacting multifunctional protein 3;Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3;ARS interacting multifunctional protein 3;EEF1E1;Elongation factor p18;Eukaryotic translation elongation factor 1 epsilon 1;Eukaryotic translation elongation factor 1 epsilon-1;Homolog of rat elongation factor p18;MCA3;Multisynthase complex auxiliary component p18;Multisynthetase complex auxiliary component p18;p18;p18 component of aminoacyl tRNA synthetase complex

Research Areas:Cancer;Cell Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:O43324

Accession:

Background:This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

Concentration:0.8 mg/mL

Immunogen:Full length fusion protein

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW:20 kDa

ObservedMW:Refer to figures