ECE2 Polyclonal Antibody

SKU: BT-AP15356

Size:100μL

Background:This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants.

Research_area:Cardiovascular; Neuroscience; Signal transduction

Target_protein:ECE2

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Endothelin-converting enzyme 2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: O60344; Mouse: Q80Z60

Synonyms:Endothelin-converting enzyme 2 ;ECE-2 [Includes: Methyltransferase-like region ;EC 2.1.1.-; Endothelin-converting enzyme 2 region ;EC 3.4.24.71]

GeneID:Human: 9718