DUSP8 Antibody - Cat. #: CSB-PA132342

SKU: CSB-PA132342

Size :50ul

Clone Number:

Aliases:C11orf81 antibody; Chromosome 11 open reading frame 81 antibody; Deubiquitinating enzyme 8 antibody; Dual Specificity Phosphatase 8 antibody; Dual specificity phosphatase M3/6 antibody; Dual specificity protein phosphatase 8 antibody; Dual specificity protein phosphatase hVH 5 antibody; Dual specificity protein phosphatase hVH-5 antibody; DUS8 antibody; DUS8_HUMAN antibody; DUSP8 antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; FLJ42476 antibody; FLJ42958 antibody; H1 phosphatase vaccinia virus homolog antibody; H1 phosphatase; vaccinia virus; homolog of antibody; HB5 antibody; hUBPy antibody; HVH5 antibody; HVH8 antibody; M3/6; mouse; homolog of antibody; Neuronal tyrosine threonine phosphatase 1 antibody; Serine/threonine specific protein phosphatase antibody; Ubiquitin carboxyl terminal hydrolase 8 antibody; Ubiquitin specific processing protease 8 antibody; Ubiquitin thiolesterase 8 antibody; VH5 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13202

Immunogen:Synthetic peptide of Human DUSP8

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:50-1:200

Background:The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DUSP8

Research Areas:Signal transduction