DNMT3L antibody , Cat. # FNab02486

SKU: FNab02486

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4(H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.

Immunogen:DNA(cytosine-5-)-methyltransferase 3-like

Synonyms:

Observed MW:44kd and 70kd

Uniprot ID:Q9UJW3

Reactivity:Human

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:2000

Gene ID:29947

Research Area:Epigenetics, Metabolism, Developmental biology