DNAJC10 Antibody, HRP conjugated - Cat. #: CSB-PA809006LB01HU

SKU: CSB-PA809006LB01HU

Size :50ul

Clone Number:

Aliases:DNAJC10 antibody; ERDJ5 antibody; UNQ495/PRO1012DnaJ homolog subfamily C member 10 antibody; EC 1.8.4.- antibody; Endoplasmic reticulum DNA J domain-containing protein 5 antibody; ER-resident protein ERdj5 antibody; ERdj5 antibody; Macrothioredoxin antibody; MTHr antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8IXB1

Immunogen:Recombinant Human DnaJ homolog subfamily C member 10 protein (521-793AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DNAJC10

Research Areas:Signal transduction