DNA2 Polyclonal Antibody

SKU: BT-AP15255

Size:100μL

Background:This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene.

Research_area:Epigenetics and nuclear signaling

Target_protein:DNA2

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:DNA replication ATP-dependent helicase/nuclease DNA2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P51530; Mouse: Q6ZQJ5; Rat: D3ZG52

Synonyms:DNA replication ATP-dependent helicase/nuclease DNA2 ;hDNA2;DNA replication ATP-dependent helicase-like homolog [Includes: DNA replication nuclease DNA2 ;EC 3.1.-.-; DNA replication ATP-dependent

GeneID:Human: 1763