DMRT2 rabbit pAb

SKU: ES16928

Size: 100μL

Source:Rabbit

Applications:WB

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000

Immunogen:Synthesized peptide derived from human DMRT2 AA range: 315-365

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):60kD

Human_gene_id:10655

Human_swiss_prot_no:Q9Y5R5

Subcellular_location:Nucleus .

Other_name:Doublesex- and mab-3-related transcription factor 2 (Doublesex-like 2 protein) (DSXL-2)

Background:The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010],