DMPK Antibody, Biotin conjugated - Cat. #: CSB-PA006968LD01HU

SKU: CSB-PA006968LD01HU

Size :50ug

Clone Number:

Aliases:DM 1 antibody; DM antibody; DM kinase antibody; DM protein kinase antibody; DM-kinase antibody; DM1 antibody; DM1 protein kinase antibody; DM1PK antibody; DMK antibody; DMPK antibody; DMPK_HUMAN antibody; Dystrophia myotonica 1 antibody; Dystrophia myotonica protein kinase antibody; MDPK antibody; MT PK antibody; MT-PK antibody; Myotonic dystrophy associated protein kinase antibody; Myotonic dystrophy protein kinase antibody; Myotonin protein kinase A antibody; Myotonin protein kinase antibody; Myotonin-protein kinase antibody; Thymopoietin homolog antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q09013

Immunogen:Recombinant Human Myotonin-protein kinase protein (243-424AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeostasis. Phosphorylates PLN, a regulator of calcium pumps and may regulate sarcoplasmic reticulum calcium uptake in myocytes. May also phosphorylate FXYD1/PLM which is able to induce chloride currents. May also play a role in synaptic plasticity.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DMPK

Research Areas:Neuroscience; Signal transduction