DLC1 Antibody - Cat. #: CSB-PA124374

SKU: CSB-PA124374

Size :100ul

Clone Number:

Aliases:ARHGAP 7 antibody; ARHGAP7 antibody; Deleted in liver cancer 1 antibody; Deleted in liver cancer 1 protein antibody; DLC 1 antibody; Dlc-1 antibody; DLC1 antibody; DLC1 Rho GTPase activating protein antibody; FLJ21120 antibody; HP antibody; HP protein antibody; KIAA1723 antibody; p122 RhoGAP antibody; RHG07_HUMAN antibody; Rho GTPase activating protein 7 antibody; Rho GTPase-activating protein 7 antibody; Rho type GTPase activating protein 7 antibody; Rho-type GTPase-activating protein 7 antibody; StAR related lipid transfer (START) domain containing 12 antibody; StAR related lipid transfer protein 12 antibody; StAR-related lipid transfer protein 12 antibody; STARD 12 antibody; StARD12 antibody; START domain containing protein 12 antibody; START domain-containing protein 12 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96QB1

Immunogen:Synthesized peptide derived from internal of Human RHG07.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC, IF; IHC:1:50-1:100, IF:1:100-1:500

Background:Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.

Yuan B.Z., Cancer Res. 58:2196-2199(1998).
Nagase T., DNA Res. 7:347-355(2000).
Wilson P.J., Hum. Mutat. 15:156-165(2000).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DLC1

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Tags & Cell Markers;Signal transduction