DCX Antibody - Cat. #: CSB-PA189299

SKU: CSB-PA189299

Size :100ul

Clone Number:

Aliases:DBCN antibody; Dbct antibody; DC antibody; DCX antibody; DCX_HUMAN antibody; Doublecortex antibody; Doublin antibody; FLJ51296 antibody; Lis X antibody; Lis-X antibody; Lissencephalin X antibody; Lissencephalin-X antibody; Lissencephaly X linked antibody; Lissencephaly X linked doublecortin antibody; LISX antibody; Neuronal migration protein doublecortin antibody; OTTHUMP00000023859 antibody; OTTHUMP00000023860 antibody; OTTHUMP00000216315 antibody; OTTHUMP00000216316 antibody; SCLH antibody; XLIS antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O43602

Immunogen:Peptide sequence around aa.413~417( P-T-S-P-G) derived from Human Doublecortin.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.

Des Portes V., Pinard J.-M., Billuart P. Chelly J.Cell 92:51-61(1998)
Pilz D.T., Matsumoto N., Minnerath S.R., Mills P. Hum. Mol. Genet. 7:2029-2037(1998)

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DCX

Research Areas:Neuroscience;Tags & Cell Markers