CYP1A1 Monoclonal Antibody

SKU: BT-MCA4492

Size:100μL

Background:This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

Research_area:Others

Target_protein:CYP1A1

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:6G5

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CYP1A1

Immunogen:Purified recombinant fragment of human CYP1A1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):58kDa

UniProt accession:P04798

Synonyms:AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX

GeneID:1543