CYFIP1 Antibody, HRP conjugated - Cat. #: CSB-PA748722LB01HU

SKU: CSB-PA748722LB01HU

Size :50ug

Clone Number:

Aliases:CY antibody; CYFIP 1 antibody; CYFIP1 antibody; CYFP1_HUMAN antibody; Cytoplasmic FMR1 interacting protein 1 antibody; Cytoplasmic FMR1-interacting protein 1 antibody; FLJ45151 antibody; KIAA0068 antibody; p140sra 1 antibody; p140sra-1 antibody; P140SRA1 antibody; Selective hybridizing clone antibody; SHYC antibody; Specifically Rac1 associated protein 1 antibody; Specifically Rac1-associated protein 1 antibody; SRA 1 antibody; Sra-1 antibody; SRA1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q7L576

Immunogen:Recombinant Human Cytoplasmic FMR1-interacting protein 1 protein (320-449AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). May act as an invasion suppressor in cancers.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CYFIP1

Research Areas:Others