CRM1 Rabbit Polyclonal Antibody

SKU: BT-AP08460

Size:100μL

Background:This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B| MPAK| and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

Research_area:Epigenetics and nuclear signaling; Signal transduction

Target_protein:XPO1

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:CRM1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):117810

UniProt accession:Human: O14980; Mouse: Q6P5F9; Rat: Q80U96

Synonyms:CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog

GeneID:Human: 7514; Mouse: 103573; Rat: 85252