COL1A2 Antibody - Cat. #: CSB-PA201854

SKU: CSB-PA201854

Size :50ul

Clone Number:

Aliases:Alpha 2 collagen type I antibody; Alpha 2 type I collagen antibody; Alpha 2 type I procollagen antibody; Alpha 2(I) collagen antibody; Alpha 2(I) procollagen antibody; Alpha-2 type I collagen antibody; CO1A2_HUMAN antibody; COL1A2 antibody; Collagen alpha 2(I) chain antibody; Collagen alpha-2(I) chain antibody; Collagen I alpha 2 polypeptide antibody; Collagen of skin tendon and bone alpha 2 chain antibody; Collagen type I alpha 2 antibody; OI4 antibody; Osteogenesis imperfecta type IV antibody; Type I procollagen antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P08123

Immunogen:Fusion protein of Human COL1A2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:COL1A2

Research Areas:Signal transduction?Stem cells