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Gene Bio Systems

COL18A1 Antibody - Cat. #: CSB-PA199023

COL18A1 Antibody - Cat. #: CSB-PA199023

SKU:CSB-PA199023

Regular price $415.00 USD
Regular price Sale price $415.00 USD
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Size :50ul

Clone Number:

Aliases:Alpha 1 collagen type 18 (XVIII)(COL18A1) antibody; Alpha 1 type XVIII collagen antibody; Antiangiogenic agent antibody; COIA1_HUMAN antibody; COL15A1 antibody; Col18a1 antibody; Collagen alpha 1(XV) chain antibody; Collagen alpha 1(XVIII) chain antibody; Collagen alpha-1(XV) chain antibody; Collagen type XV proteoglycan antibody; Collagen type XVIII alpha 1 antibody; Collagen XV; alpha 1 polypeptide antibody; Collagen; type XV; alpha 1 antibody; Endostatin antibody; Endostatin XV antibody; FLJ27325 antibody; FLJ34914 antibody; FLJ38566 antibody; KNO antibody; KNO1 antibody; KS antibody; MGC74745 antibody; Multi functional protein MFP antibody; OTTHUMP00000021782 antibody; OTTHUMP00000115472 antibody; OTTHUMP00000115473 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P39060

Immunogen:Synthetic peptide of Human COL18A1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:100-1:300

Background:This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:COL18A1

Research Areas:Cancer?Cardiovascular;Signal transduction

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