CNTN1 Antibody, Biotin conjugated - Cat. #: CSB-PA623657LD01HU

SKU: CSB-PA623657LD01HU

Size :50ug

Clone Number:

Aliases:CNTN 1 antibody; CNTN antibody; Cntn1 antibody; CNTN1_HUMAN antibody; Contactin-1 antibody; Contactin1 antibody; F3 antibody; F3cam antibody; Glycoprotein gp135 antibody; gp 135 antibody; GP135 antibody; MYPCN antibody; Neural cell surface protein F3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q12860

Immunogen:Recombinant Human Contactin-1 protein (686-866AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CNTN1

Research Areas:Neuroscience