CMKLR1 Antibody - Cat. #: CSB-PA005614LA01HU

SKU: CSB-PA005614LA01HU

Size :50ug

Clone Number:

Aliases:CHEMERINR antibody; Chemokine like receptor 1 antibody; Chemokine-like receptor 1 antibody; CHEMR23 antibody; CMKLR1 antibody; CML1_HUMAN antibody; DEZ antibody; G protein coupled receptor ChemR23 antibody; G protein coupled receptor DEZ antibody; G-protein coupled receptor ChemR23 antibody; G-protein coupled receptor DEZ antibody; Orphan G protein coupled receptor antibody; Orphan G protein coupled receptor Dez antibody; Resolvin E1 receptor antibody; RVER1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q99788

Immunogen:Recombinant Human Chemokine-like receptor 1 protein (321-373AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background:Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CMKLR1

Research Areas:Cell biology; Signal transduction