Cleaved-SUMO-2/3 (G93) rabbit pAb

SKU: ES1054

Size: 100μL

Source:Rabbit

Applications:WB;ELISA;CoIP

Reactivity:Human;Mouse;Rat

Dilution:Western Blot: 1/500 - 1/2000. ELISA: 1/20000. IP 1:50-100 Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human SUMO2/3. AA range:44-93

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):11kD

Human_gene_id:6613

Human_swiss_prot_no:P61956

Subcellular_location:Nucleus. Nucleus, PML body.

Other_name:SUMO2; SMT3A; SMT3H2; Small ubiquitin-related modifier 2; SUMO-2; HSMT3; SMT3 homolog 2; SUMO-3; Sentrin-2; Ubiquitin-like protein SMT3A; Smt3A

Background:This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],