CHRNA9 Antibody - Cat. #: CSB-PA887022ESR2HU

SKU: CSB-PA887022ESR2HU

Size :50ul

Clone Number:

Aliases:CHRNA9 antibody; NACHRA9Neuronal acetylcholine receptor subunit alpha-9 antibody; Nicotinic acetylcholine receptor subunit alpha-9 antibody; NACHR alpha-9 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UGM1

Immunogen:Recombinant Human Neuronal acetylcholine receptor subunit alpha-9 protein (26-240AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane (PubMed:11752216, PubMed:25282151). The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane (PubMed:11752216, PubMed:25282151). In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion (PubMed:11021840).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CHRNA9

Research Areas:Neuroscience