CERS6 Antibody - Cat. #: CSB-PA150016

SKU: CSB-PA150016

Size :50ul

Clone Number:

Aliases:Ceramide synthase 6 antibody; CerS 6 antibody; CERS5 antibody; CerS6 antibody; LAG1 homolog ceramide synthase 6 antibody; LAG1 longevity assurance homolog 6 antibody; LASS 6 antibody; Lass6 antibody; LASS6_HUMAN antibody; Longevity assurance homolog 6 antibody; MGC129949 antibody; MGC129950 antibody; T1L antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q6ZMG9

Immunogen:Synthetic peptide of Human CERS6

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they all are involved in sphingolipid synthesis. LASS6 is a widely expressed 384 amino acid endoplasmic reticulum, multi-pass membrane protein. On the luminal side of the endoplasmic reticulum membrane, the N-terminal asparagine residue is glycosylated. In cells deficient for CLN9, LASS6 corrects growth and apoptosis, and increases the levels of short ceramide species, such as C14:0- and C16:0-ceramides.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CERS6

Research Areas:Cancer;Metabolism;Signal transduction