CEACAM1/CD66a Monoclonal Antibody

SKU: AN200110P

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:CEACAM1

Target Synonym:Biliary Glycoprotein;Carcinoembryonic Antigen-Related Cell Adhesion Molecule;CEACAM;CEACAM1;BGP;BGP1;BGPI;BGP-1;Biliary Glycoprotein 1;Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1;CD66a;NCA-160;Antigen CD66;BGP 1;Biliary glycoprotein adhesion molecule;Carcinoembryonic antigen related cell adhesion molecule 1;carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein);CD66a antigen;CEAM1;meconium antigen 100

Research Areas:Tags & Cell Markers;Immunology;Cancer;Microbiology

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:IHC-P;FCM

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:8C12

UNIProt ID:P13688

Accession:

Background:This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Concentration:1 mg/mL

Immunogen:Recombinant Human CD66a protein

Buffer:0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0

Purification method:Protein A

Dilution:IHC-P 1:50-1:200;FCM 1:25-1:100;

Calculated MW:

ObservedMW: