Cdk9 (Acetyl Lys44) Rabbit Polyclonal Antibody

SKU: BT-AP01333

Size:100μL

Background:The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28| and S. pombe cdc2| and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb| which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T| which suggested a possible involvement of this protein in AIDS.

Research_area:Cell biology; Epigenetics and nuclear signaling; Immunology; Microbiology

Target_protein:CDK9

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Cdk9

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):40920

UniProt accession:Human: P50750; Mouse: Q99J95; Rat: Q641Z4

Synonyms:Cdk9 ;Acetyl Lys44; Cyclin-dependent kinase 9; EC 2.7.11.22; EC 2.7.11.23; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit

GeneID:Human: 1025; Mouse: 107951; Rat: 362110