CDH16 Monoclonal Antibody

SKU: BT-MCA3873

Size:100μL

Background:This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Research_area:Signal Transduction

Target_protein:CDH16

applications:WB, IHC, ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:6H6E2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CDH16

Immunogen:Purified recombinant fragment of human CDH16 (AA: EX(558-721)) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):90kDa

UniProt accession:O75309

Synonyms:KSP-Cadherin

GeneID:1014