Cdc25A(Phospho Ser75) Polyclonal Antibody

SKU: BT-AP07488

Size:100μL

Background:CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Research_area:Cancer; Cell biology; Epigenetics and nuclear signaling

Target_protein:CDC25A

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:M-phase inducer phosphatase 1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):59087

UniProt accession:Human: P30304; Mouse: P48964; Rat: P48965

Synonyms:M-phase inducer phosphatase 1; CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A

GeneID:Human: 993; Rat: 171102