CD45 Monoclonal Antibody

SKU: E-AB-22009

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Monoclonal Antibodies

Abbreviation: CD45

Target Synonym: B220;CD 45;CD45;CD45 antigen;CD45R;GP180;L-CA;LCA;Leukocyte common antigen;loc;Ly-5;LY5;Ly5;homolog of;Lyt-4;OTTHUMP00000033813;OTTHUMP00000033816;OTTHUMP00000033817;OTTHUMP00000038574;Protein tyrosine phosphatase receptor type c polypeptide;Protein tyrosine phosphatase;receptor type C;protein tyrosine phosphatase;receptor type;C;Protein tyrosine phosphatase;receptor type;c polypeptide;Ptprc;PTPRC;Receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen

Research Areas: Cancer;Cardiovascular;Immunology;Neuroscience;Signal Transduction;Stem Cells

Conjugation: Unconjugated

Host: Mouse

Species reactivity: Human

Application: WB;IHC-p

Isotype: IgG

Clonality: Monoclonal

Clone NO.: Clone:3H3

UNIProt ID: P08575

Accession:

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.

Concentration: 1 mg/mL

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification method: Protein A purification

Dilution: WB 1:500-1:2000;IHC 1:50-300

Calculated MW: 147kDa

ObservedMW: 147kDa