CD33 Antibody - Cat. #: CSB-PA004925ESR2HU

SKU: CSB-PA004925ESR2HU

Size :50ul

Clone Number:

Aliases:CD 33 antibody; CD33 antibody; CD33 antigen (gp67) antibody; CD33 antigen antibody; CD33 molecule antibody; CD33_HUMAN antibody; FLJ00391 antibody; gp67 antibody; My9 antibody; Myeloid cell surface antigen CD33 antibody; Myeloid cell surface antigen CD33 precursor antibody; Myeloid differentiation antigen CD33 antibody; p67 antibody; Sialic acid binding Ig like lectin 3 antibody; Sialic acid binding immunoglobulin like lectin 3 antibody; Sialic acid-binding Ig-like lectin 3 antibody; SIGLEC 3 antibody; Siglec-3 antibody; SIGLEC3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P20138

Immunogen:Recombinant Human Myeloid cell surface antigen CD33 protein (49-259AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CD33

Research Areas:Immunology; Stem cells