CD217 Monoclonal Antibody

SKU: BT-MCA2804

Size:100μL

Background:Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research_area:Others

Target_protein:CD217

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:6H1B1

Host:Mouse

Isotype:Mouse IgG2b

Gene Symbol/ Name:CD217

Immunogen:Purified recombinant fragment of human CD217 (AA: extra 33-320) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):96.1kDa

UniProt accession:Q96F46

Synonyms:IL17RA, IL17R, IMD51, CANDF5, CDw217, IL-17RA, hIL-17R

GeneID:23765