CD215 Monoclonal Antibody

SKU: BT-MCA4217

Size:100μL

Background:This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010]

Research_area:Others

Target_protein:CD215

applications:WB

Reactivity:

Clonality:Monoclonal

Clone ID:5F10D9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CD215

Immunogen:Purified recombinant fragment of human CD215 (AA: extra 31-205) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):28.2kDa

UniProt accession:Q13261

Synonyms:IL15RA

GeneID:3601