CD16 antibody , Cat. # FNab10139

SKU: FNab10139

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors Fc?RIIIa (CD16a) and Fc?RIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B.

Immunogen:Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

Synonyms:CD16, CD16A, CD16a antigen, Fc gamma RIII, Fc gamma RIII alpha, Fc gamma RIIIa, FCG3, FCGR3, FCGR3A, FCGRIII, FCR 10, FCRIII, FCRIIIA, IGFR3, IgG Fc receptor III 2

Observed MW:55 kDa

Uniprot ID:P08637

Reactivity:Human

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:200-1:2000; IHC: 1:50-1:200

Gene ID:2214

Research Area:Signal Transduction, Cardiovascular, Immunology, Cancer, Stem Cells