CCNF Antibody - Cat. #: CSB-PA906292

SKU: CSB-PA906292

Size :100ul

Clone Number:

Aliases:Ccnf antibody; CCNF_HUMAN antibody; Cyclin-F antibody; F box only protein 1 antibody; F-box only protein 1 antibody; FBX1 antibody; FBXO1 antibody; G2 mitotic specific cyclin F antibody; G2/mitotic specific cyclin F antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P41002

Immunogen:Synthesized peptide derived from Human Cyclin F.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication.

Tsz Kan Fung, J. Biol. Chem., Sep 2002; 277: 35140 - 35149.
Michael T. Tetzlaff, Mol. Cell. Biol., Mar 2004; 24: 2487 - 2498.
Cain H. Yam, Mol. Cell. Biol., Jan 1999; 19: 635 - 645.
Michael T. Tetzlaff, PNAS, Mar 2004; 101: 3338 - 3345.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CCNF

Research Areas:Cell biology