CARM1 Monoclonal Antibody

SKU: BT-MCA4454

Size:100μL

Background:Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al. 2002 (PubMed 11724789). Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.

Research_area:Epigenetics and nuclear signaling, Cell biology, Cancer, Metabolism, Signal transduction

Target_protein:CARM1

applications:WB, IHC, ICC, FCM

Reactivity:Human, Monkey, Rat

Clonality:Monoclonal

Clone ID:3H2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CARM1

Immunogen:Purified recombinant fragment of human CARM1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):65kDa

UniProt accession:Q86X55

Synonyms:PRMT4, CARM1

GeneID:10498