CARD16 Polyclonal Antibody

SKU: E-AB-17810

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CARD16

Target Synonym: CAR16;CARD only domain-containing protein 1;CARD only protein ;CARD16;Caspase recruitment domain family; member 16;Caspase recruitment domain-containing protein 16;Caspase-1 dominant-negative inhibitor pseudo-ICE ;Caspase-1 inhibitor COP;COP;COP1;Pseudo interleukin 1 beta converting enzyme;Pseudo interleukin-1 beta converting enzyme;Pseudo interleukin-1beta converting enzyme ;PSEUDO-ICE

Research Areas: Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q5EG05

Accession:

Background: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

Concentration: 1.1 mg/mL

Immunogen: Synthetic peptide of human CARD16

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:40-1:200

Calculated MW: 23 kDa

ObservedMW: Refer to figures