CAPN6 Antibody - Cat. #: CSB-PA559356

SKU: CSB-PA559356

Size :50ul

Clone Number:

Aliases:CALP M antibody; Calpain-6 antibody; Calpain-like protease X-linked antibody; Calpamodulin antibody; CalpM antibody; CAN6_HUMAN antibody; CANP X antibody; CANPX antibody; CAPN 6 antibody; Capn6 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y6Q1

Immunogen:Fusion protein of Human CAPN6

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:25-1:100

Background:Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CAPN6

Research Areas:Cell biology;Signal transduction