Canine Caspase-3, CASP3 ELISA Kit

SKU: E0334Ca

Size:96 Tests-1 Kit

Background:Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. Cleaves and inhibits serine/threonine-protein kinase AKT1 in response to oxidative stress.

Research_area:Others

Applications:ELISA

Target_protein:CASP3

Reactivity:Canine

Assay type:Sandwich

Sensitivity:0.15ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Caspase-3

Species:Canine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8MKI5

MASS(Da):31,335

GeneID:403567

Synonyms:CASP 3;CASP3;CASP-3;Caspase-3;Caspase-3 subunit p12;Caspase-3 subunit p17

Gene names:CASP3

Standard solution:96ng/mL