CABLES1 Antibody - Cat. #: CSB-PA138718

SKU: CSB-PA138718

Size :100ul

Clone Number:

Aliases:CABL1_HUMAN antibody; CABLES antibody; Cables1 antibody; Cdk5 and Abl enzyme substrate 1 antibody; CDK5 and ABL1 enzyme substrate 1 antibody; FLJ35924 antibody; HsT2563 antibody; IK3 1 antibody; Ik3-1 antibody; Interactor with CDK3 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8TDN4

Immunogen:Synthesized peptide derived from internal of Human Ik3-1.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death By similarity.

Ota T., Nat. Genet. 36:40-45(2004).
Nusbaum C., Nature 437:551-555(2005).
Wu C.-L., Cancer Res. 61:7325-7332(2001).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CABLES1

Research Areas:Cell biology