Bovine Tissue inhibitor of metalloproteinases 1,TIMP-1 ELISA KIT

SKU: E0007Bo

Size:96Tests

Background:Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. {ECO:0000269|PubMed:8199264, ECO:0000269|PubMed:8417953}.

Research_area:

Applications:ELISA

Target_protein:TIMP1

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:0.05ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Tissue inhibitors of metalloproteinase 1

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P20414

MASS(Da):23032

GeneID:282092

Synonyms:TIMP1

Gene names:TIMP1

Standard solution:48ng/ml