Bovine Interleukin 21,IL-21 ELISA KIT

SKU: E0102Bo

Size:96Tests

Background:Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity). {ECO:0000250|UniProtKB:Q9ES17, ECO:0000250|UniProtKB:Q9HBE4}.

Research_area:

Applications:ELISA

Target_protein:IL21

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:0.29ng/ml

Detection range:0.5-32ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Interleukin 21

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q76LU5

MASS(Da):17690

GeneID:378475

Synonyms:IL21

Gene names:IL21

Standard solution:64ng/ml