Bovine Caspase 3, CASP3 ELISA Kit

SKU: E2192Bo

Size:96 Tests-1 Kit

Background:Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. Cleaves and inhibits serine/threonine-protein kinase AKT1 in response to oxidative stress.

Research_area:Cell Biology; Cancer; Metabolism

Applications:ELISA

Target_protein:CASP3

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:0.048ng/mL

Detection range:0.1-40ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Caspase 3

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q08DY9

MASS(Da):31,136

GeneID:408016

Synonyms:CASP 3;CASP3;CASP-3;Caspase-3;Caspase-3 subunit p12;Caspase-3 subunit p17

Gene names:CASP3

Standard solution:48ng/mL