Bovine Acyl-CoA Desaturase, SCD ELISA Kit

SKU: E2185Bo

Size:96 Tests-1 Kit

Background:Involved in the biosynthesis of highly unsaturated fatty acids (HUFA) from the essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) precursors, acting as a fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 6 of the fatty acyl chain. Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleate (GLA) (18:3n-6) and stearidonate (18:4n-3), respectively (By similarity). Subsequently, in the biosynthetic pathway of HUFA n-3 series, it desaturates tetracosapentaenoate (24:5n-3) to tetracosahexaenoate (24:6n-3), which is then converted to docosahexaenoate (DHA)(22:6n-3), an important lipid for nervous system function (By similarity). It can also desaturate (11E)-octadecenoate (trans-vaccenoate, a metabolite in the biohydrogenation pathway of LA and the predominant trans fatty acid in cow milk) at carbon 6 generating (6Z,11E)-octadecadienoate (By similarity). In addition to Delta-6 activity, this enzyme exhibits Delta-8 activity with slight biases toward n-3 fatty acyl-CoA substrates (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:SCD

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:9.81ng/L

Detection range:20-3800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Acyl-CoA desaturase

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:A4FV48

MASS(Da):52,533

GeneID:521822

Synonyms:Acyl-CoA 6-desaturase;D6D;Delta(6 desaturase;Delta(6 fatty acid desaturase;Delta-6 desaturase;Fatty acid desaturase 2;SCD

Gene names:FADS2

Standard solution:4000ng/L