Beclin-1 (5C2) Mouse mAb

SKU: EM1304

Size: 100μL

Source:Mouse

Applications:WB, IHC

Reactivity:Human, Rat, Mouse

Dilution:WB 1:1,000-2,000 IHC 1:100-200

Immunogen:Synthetic Peptide

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):60kDa

Human_gene_id:8678

Human_swiss_prot_no:Q14457

Subcellular_location:Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane, Mitochondrion, Nucleus

Other_name:ATG6, Bcl-2 interacting protein beclin, BECN1, Coiled coil myosin like BCL2 interacting protein

Background:Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of proteins activated in response to nutrient deprivation and in neurodegenerative conditions. One of the proteins critical to this process is Beclin-1.