BCOR Antibody, FITC conjugated - Cat. #: CSB-PA761519LC01HU

SKU: CSB-PA761519LC01HU

Size :50ug

Clone Number:

Aliases:5830466J11Rik antibody; 8430401K06Rik antibody; ANOP 2 antibody; ANOP2 antibody; BCL 6 co repressor antibody; BCL 6 corepressor antibody; BCL 6 interacting corepressor antibody; BCL-6 corepressor antibody; BCL6 co repressor antibody; BCL6 corepressor antibody; BCL6 interacting corepressor antibody; BCoR antibody; BCOR_HUMAN antibody; FLJ20285 antibody; FLJ38041 antibody; KIAA1575 antibody; MAA 2 antibody; MAA2 antibody; MCOPS 2 antibody; MCOPS2 antibody; MGC131961 antibody; MGC71031 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q6W2J9

Immunogen:Recombinant Human BCL-6 corepressor protein (1569-1755AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 \'Lys-4\' (H3K4me3) and \'Lys-36\' (H3K36me2).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:BCOR

Research Areas:Epigenetics and Nuclear Signaling