BANF1 Antibody, Biotin conjugated - Cat. #: CSB-PA002550LD01HU

SKU: CSB-PA002550LD01HU

Size :50ug

Clone Number:

Aliases:BAF antibody; BAF_HUMAN antibody; BANF 1 antibody; BANF1 antibody; Barrier to autointegration factor 1 antibody; Barrier to autointegration factor antibody; Barrier-to-autointegration factor antibody; BCRG 1 antibody; BCRG1 antibody; BCRP 1 antibody; BCRP1 antibody; Breakpoint cluster region protein 1 antibody; D14S1460 antibody; MGC111161 antibody; NGPS antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O75531

Immunogen:Recombinant Human Barrier-to-autointegration factor protein (2-89AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:BANF1

Research Areas:Microbiology