BAD Polyclonal Antibody

SKU: E-AB-70084

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:BAD

Target Synonym:AI325008;BAD;BAD;BBC 2;BBC2;BBC6;Bcl 2 Antagonist of Cell Death;Bcl 2 Binding Component 6;BCL X / BCL 2 Binding Protein;BCL X Binding Protein;Bcl XL/Bcl 2 Associated Death Promoter;Bcl-2-binding component 6;Bcl-2-like protein 8;Bcl-XL/Bcl-2-associated death promoter;Bcl2 antagonist of cell death;BCL2 antagonist of cell death protein;BCL2 associated agonist of cell death;Bcl2 Associated Death Promoter;BCL2 binding component 6;BCL2 binding protein;Bcl2 Like 8 Protein;Bcl2-L-8;BCL2L8;Proapoptotic BH3 Only Protein

Research Areas:Cancer;Cell Biology;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q92934,Q61337,O35147

Accession:

Background:The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Concentration:300 μg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse Bad

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:IHC 1:300

Calculated MW:

ObservedMW: