BABAM2 Polyclonal Antibody

SKU: E-AB-11008

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: BRE

Target Synonym: 6030405P19Rik;AI429776;B830038C02Rik;Brain and reproductive organ expressed (TNFRSF1A modulator);brain and reproductive organ expressed protein;Brain and reproductive organ-expressed protein;BRCA1 A complex subunit BRE;BRCA1-A complex subunit BRE;BRCA1/BRCA2 containing complex subunit 4;BRCA1/BRCA2 containing complex subunit 45;BRCA1/BRCA2-containing complex subunit 45;BRCC4;BRCC45;bre;BRE

Research Areas: Cancer;Cell Biology;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9NXR7

Accession:

Background: Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellular juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1). BRE also binds to the death receptor, FAS. BRE downregulates TNFa-induced activation of NFkB and may play a role in homeostasis or cellular differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medulla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine.

Concentration: 0.5 mg/mL

Immunogen: Recombinant protein of human BRE

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 44kDa

ObservedMW: