AURKAIP1 Antibody - Cat. #: CSB-PA794202

SKU: CSB-PA794202

Size :50ul

Clone Number:

Aliases:28S ribosomal protein S38 antibody; AIP antibody; AKIP_HUMAN antibody; AURKA interacting protein antibody; AURKA-interacting protein antibody; AURKAIP 1 antibody; Aurkaip1 antibody; Aurora A kinase interacting protein antibody; Aurora kinase A interacting protein 1 antibody; Aurora kinase A-interacting protein antibody; FLJ20608 antibody; mitochondrial antibody; MRP-S38 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NWT8

Immunogen:Fusion protein of Human AURKAIP1

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000

Background:AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:AURKAIP1

Research Areas:Cancer;Cell biology