AUP1 Monoclonal Antibody

SKU: BT-MCA4577

Size:100μL

Background:The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.

Research_area:Others

Target_protein:AUP1

applications:WB

Reactivity:Human, Mouse

Clonality:Monoclonal

Clone ID:1H6A1

Host:Mouse

Isotype:Mouse IgG2b

Gene Symbol/ Name:AUP1

Immunogen:Purified recombinant fragment of human AUP1 (AA: 229-410) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):53kDa

UniProt accession:Q9Y679

Synonyms:

GeneID:550