ASIC3 Antibody - Cat. #: CSB-PA890688ESR1HU

SKU: CSB-PA890688ESR1HU

Size :50ul

Clone Number:

Aliases:ACCN 3 antibody; Accn3 antibody; ACCN3_HUMAN antibody; Acid sensing ion channel 3 antibody; Acid-sensing ion channel 3 antibody; Amiloride sensitive cation channel 3 antibody; Amiloride sensitive cation channel 3 testis antibody; Amiloride-sensitive cation channel 3 antibody; ASIC 3 antibody; ASIC3 antibody; DRASIC antibody; hASIC 3 antibody; hASIC3 antibody; hTNaC 1 antibody; hTNaC1 antibody; Modulatory subunit of ASIC 2a antibody; Modulatory subunit of ASIC2a antibody; Neuronal amiloride sensitive cation channel 3 antibody; Neuronal amiloride-sensitive cation channel 3 antibody; Proton gated cation channel subunit antibody; SLNAC 1 antibody; SLNAC1 antibody; Testis sodium channel 1 antibody; TNaC 1 antibody; TNaC1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UHC3

Immunogen:Recombinant Human Acid-sensing ion channel 3 protein (62-320AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ASIC3

Research Areas:Neuroscience